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DR. BRODSKIY’S GUIDE · AESTHETIC MEDICINE

Collagen-Stimulating Injections: Why Results Take Time

Raya Brodskiy, MD

Collagen is a protein that helps support your skin. Think of it as part of the skin’s inner frame. Some injections aim to help the body make more collagen over time.

You may hear these called biostimulators. That means they trigger a response in the body. This group includes different materials. They do not all work the same way.

What is PLLA?

One example is poly-L-lactic acid, or PLLA. It is made of tiny particles that the body slowly breaks down. The body may make new collagen around the treated area as this happens.

This guide focuses on PLLA. Other collagen-stimulating products, such as those made with calcium hydroxylapatite, need their own treatment plan.

Why does the change take time?

Making collagen is a slow process. PLLA results build over weeks to months. More than one visit may be needed.

Fullness seen right after treatment may come from the fluid used with the product or from swelling. That early look is not the final result.

Follow-up visits help your provider judge the change before adding more. Ask when to expect a fair check of your result.

How is this different from HA filler?

HA filler adds volume with a gel. PLLA relies more on a gradual response in your tissue.

PLLA cannot be dissolved with the enzyme used for HA filler. If a problem occurs, care may be more involved. Ask about this difference before choosing treatment.

What are the risks?

You may have swelling, bruising, redness, or soreness. Lumps can form under the skin, sometimes later on. They may need medicine or another procedure. Infection and allergic reactions can also occur.

As with other facial fillers, a rare injection into a blood vessel can cause serious harm, including skin damage, blindness, or a stroke.

Get medical help right away for unusual pain, pale skin, a change in vision, sudden weakness, or trouble speaking during or after treatment.

What should I ask before treatment?

Ask which material is being used, why it fits your goal, and what care you will need afterward. Share your health history, medicines, allergies, and any history of thick, raised scars.

A slower result still needs a careful plan. Take time to understand the product before you decide.

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